Non-enzymatic cyclization of creatine ethyl ester to creatinine Matthew W. Giese Department of Chemistry, Marian University, 3200 Cold Spring Rd., Indianapolis, IN 46222, USA Received 28 July 2009. Available online 4 August 2009. Creatine ethyl ester was incubated at 37 °C in both water and
phosphate-buffered saline and the diagnostic methylene resonances in the 1H NMR ...