Topic profile page for Opioid receptors.
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Topic "Opioid receptors" was discussed 838 times on 80 sites in last 3 months
Started 1 month, 1 week ago (2009-10-28 06:55:48)
by tramadols
In May of 2002, Lilly ICOS reported to the American Urological Association that clinical trial testing in tramadol GENERIC overnight saturday delivery men with erectile dysfunction showed that tadalafil works for up to 36 hours, and one year later tadalafil was ...
Started 2 months, 1 week ago (2009-09-25 23:09:00)
by JLogan
Hello team! I'm preparing for my big quitting day, October 1! I know some of you folks will question why I set a date, but I have learned from past experieinces that you have to plan for this challenge. My questions is, can anyone tell me what it means when something has "moderate in vitro affinity for opioid receptors"?? I want to try Requip for the terrible RLS I get during ...
Started 2 months, 1 week ago (2009-09-26 02:00:00)
by worried878
people have RLS/restless leg syndrome/even is they never had a drug problem///for opiod users get the "twitches" due to sudden dopamine/endorphin withdrawal//similar to parkinsons if u know someone with that affliction...the brain needs time to heal when u abruptly remove endorphins/the brain needs time to catch up/heal/initially u will feel the side effects of dopamine depletion...
Started 1 month, 3 weeks ago (2009-10-09 11:03:00)
by rhollusstar
The likely reason tramadol helps some people who have depression is because it stimulates some non-opioid chemicals in the brain as well as some opioid receptors. It stimulates dopamine; plus, some research indicates it stimulates serotonin.
Started 2 months, 1 week ago (2009-09-27 11:24:00)
by Kotchy
Quote: Originally Posted by Carl Brutananadilewski nope, no drugs. I am kinda nervous, but an excited nervous. you will come up poz for the subs as they are a c2 narcotic and bind to the same opioid receptors. the fucking police UT showed i was on soma, i did'nt even know they could test for it
Started 2 months, 1 week ago (2009-09-24 00:00:00)
by Treacle
I still think that G has some action on opioid receptors. I've not had any G for months. I'm really proud. I'm not really bothered about it, any more. Of course I'd like some, but I won't get any. I think the habit has been kicked.
Started 2 months, 1 week ago (2009-09-24 00:00:00)
by sonic
I have tried snorting pure O-desmethyl-tramadol. This is the M1 metabolite in tramadol that has a high binding affinity to your opioid receptors. I didn't find it worth while. Oral administration seemed to work just as well if not better. Based on this, I would never snort tramadol itself even as a pure powder. I definitely would never snort a pressed tramadol pill.
Started 2 months, 1 week ago (2009-09-24 00:00:00)
by The Monkey Mantra
Quote: Originally Posted by Hammilton Nonsense. Peripheral mu opioid receptors do not produce noticable effects. You can down gallons of non-CNS permeable opioids like loperamide and not get any noticable effects, except pain from your torn rectum. If it targeted DOR you would definitely not have stronger CNS effects. A ...
Started 2 months, 2 weeks ago (2009-09-18 00:00:00)
by Captain.Heroin
Cocaine works on dopamine receptors directly by blocking reuptake of dopamine, and by flooding dopamine by releasing stores of it into the synapse. Heroin works on dopamine more indirectly by activating mu-opioid receptors, hence triggering a g-coupled protein receptor, and the chain reaction ends with a rush of dopamine. Quote: Originally ...
Started 2 months, 1 week ago (2009-09-24 00:00:00)
by muie
Forget about Noscapine, the most hallucinogenic opioid you will find is Demerol. Kratom is a bit fucked up as well, considering that kratom hits a lot of the same receptors Demerol does except kratom does it very gently while Demerol can do it massive. p.s. For someone with absolutley zero opiate tolerence, one and a half pods, drank in 2 portions (1 cup, half cup now and half cup 3-4hrs ...
Started 2 months, 1 week ago (2009-09-23 00:00:00)
by Proggy
Quote: Originally Posted by Unknown First, oxycodone and methadone DO have something in common. They are both mu opioid agonists. I stand corrected. I should learn more of the technicals, like which opies bind to which receptors and so on. Might keep me from saying something stupid again. They are prolly more ...
