Sure, these topics aren't exactly what I'd call "successful" but hey, they amuse ME at least... So Killer
Croc (mutated version, not just the "human with bad skin" version) versus The Lizard. My bet is on The Lizard. While Croc is super-strong, he's not Spider-man level strong, and The Lizard is usually depicted as being on-par or even stronger than Spider-man is. Plus, the Lizard has a tail, ...