Thread: PAI-1, MTHFR, & Protein S Deficiency

Congratulations on your bundle of joy!!? It makes me feel so much better when I hear stories like yours Lisa.? I can't help but feel that I'm going to have another miscarriage but I pray to God everyday the Lovenox will do the trick and it makes me feel so hopeful when I know it's worked for others.? My RE and regular OBGYN havn't mentioned anything about seeing a hematologist.? Should I be consulting one at some point?...

I agree, you do get used to them. The first time I used them, my MFM/OB suggested doing them in my thighs. I cried every day and would get these huge 4 inch round bruises. Well this go around my hematologist said I could do them in my stomach, and let me tell you the vast difference. I don't mind them anymore and I rarely get bruises. If I do, its a tiny pinhole bruise you can barely see. The end result is worth it all.

Congratulations! ?Sounds like you are definitely on the right track. ?However, I would recommend having your blood sugars checked. ?PAI-1 has a high correlation with insulin resistance which has also been linked to miscarriages. ?If you do have high sugars it's usually as simple as taking metformin or following the diabetic diet. ?I have MTHFR with high homocysteine, PAI-1 with insulin resistance, and Prothrombin G. ?(I also have some...

I am PAI-1 4G/4G as well.? I had 3 miscarriages and then they found this out. I started Lovenox the day after I found out I was pregnant again.? I just delivered her 3 weeks ago and everything went perfect!!!!? I know its scary especially at first.? I owe this little baby to lovenox.? I hope it helps you as much as it did me.? I'm ready for number 2 despite all the shots!? You get used to them.