Nice finds as the first two studies I have not seen. I used GM-CSF (brand name Leukine) instead of Neulasta as my white cell booster taking it days 2-12 after every chemo cycle and for 2-9 after my last chemo cycle.
Who knows why I continue to do well? I pulled out all the stops at the time because Herceptin was not available in the adjuvant setting at the time (even though I got it starting ...
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Started 2 months ago by Rich66
Oncology (Williston Park). 2005 Apr;19(4 Suppl 2):23-6.
Continuous low-dose GM-CSF as salvage therapy in refractory recurrent breast or female genital tract carcinoma.
Kurbacher CM , Kurbacher JA , Cramer EM , Rhiem K , Mallman PK , Reichelt R , Reinhold U , Stier U , Cree IA .
Institute of Gynecologic Oncology, Bonn Comprehensive Cancer Network, Germany. praxis.kurbacher@online....
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Rich66 replied 2 months ago
"I had to put up with the 4 months of that which is a pain in the butt."
Amazing. Butt pain is a good sign too?
Thanks for the details. I didn't realize it was different from Neupogen. Do you think this is a better way to recover wbc? (I have heard concern over wbc creating stem cells being activated too close to chemo, which then kills them.) I was actually thinking, if there wasn't a ...
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Becky replied 2 months ago
I did tons of research prior to therapy. My onc was going to do Neulasta but said he would do Leukine without hesitation. I used Leukine after all cycles, including my 4 AC treatments and the Taxol treatments. Normally, Neulasta is not given after the last chemo (since you have all the time in the world to recover). But I got 7 daily injections of Leukine to re-boost the good stuff as my onc ...
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Rich66 replied 1 month, 3 weeks ago
Becky says "a total of 77 shots of Leukine @500 mcg each."
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Rich66 replied 1 month, 3 weeks ago
Our Experts
Leisha Emens, M.D., Ph.D.
Phone: (410) 955-8964
Fax: (410) 614-8216
Titles
Associate Professor of Oncology
Schools/Degrees
M.D., Medicine, Baylor College of Medicine, Houston, TX
Ph.D., Cell Biology, Baylor College of Medicine, Houston, TX...
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Rich66 replied 1 month, 3 weeks ago
Medicina (Kaunas). 2009;45(8):600-6.
Safety and efficacy study of the recombinant granulocyte colony-stimulating factor for prevention of neutropenia and neutropenia-related complications in women with metastatic breast cancer receiving docetaxel/doxorubicin
[Article in Lithuanian]
Liutkauskiene S , Sveikata A , Juozaityte E , Characiejus D , Juodzbaliene E , Kregzdyte R , Fokas ...
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Rich66 replied 1 month, 2 weeks ago
Useful with GM-CSF?
J Immunol. 2009 Jul 1;183(1):137-44. Epub 2009 Jun 17.
Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12-dependent mechanism.
Shurin GV , Tourkova IL , Kaneno R , Shurin MR .
Department of Pathology, University of Pittsburgh Medical Center, PA 15213, USA. shuringv@upmc.edu
Antineoplastic ...
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