Itunes won't sync/recognize Iphone | Thread profile

That didn't seem to matter... It synched to the other 3 computers we have in our home- 2 macs and 1 other windows... It's just my specific configuration due to some unknown conflict- probably from one of my licensed real estate software programs? Apple engineers are trying to figure it out still! No luck... Tried all the USB ports, reexamined the msconfig, disconnected ALL windows software programs, firewalls, etc... same error...

Well I just tried plugging in the iPhone to it's own USB port on the computer rather than the USB hub, and I lost all control of my USB devices (mouse, keyboard, printer, etc) for about 15 secs. Then the devices turned back on and the iPhone started syncing. Now I can finally access iTunes! Hopefully your solution will fix this problem for good. Also a related note, will all this plugging/unplugging of my iPhone through the USB port hurt...

do you have the lastest version of iTunes? What OS are you running? Is it up-to-date? You're not running 64-bit Vista, are you?

I think the problem here is the part where you say "had it activated at the ATT store." The activation is supposed to take place using a specfic computer that it will sync to in the future. QS

Ran into this exact issue myself and found this discussion after googling 0xE8000001 and iphone. I do have a powered 7-port USB hub, and it's been working fine for months. This morning however I tried to email someone I added to my iPhone contact list yesterday and it didn't show up in Mail.app, that's when I noticed it hadn't synced. Trying the suggestions in this discussion also got me a "Device Removal"...