Merck research on UNA-modified...
Published (2009-11-19 16:13:00)
Thought this might be of interest to the mdRNA crowd. Nucleic Acids Res. 2009 Nov 16. [Epub ahead of print] Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo. Kenski DM , Cooper AJ , Li JJ , Willingham AT , Haringsma HJ , Young TA , Kuklin NA , Jones...